Bone Marrow Transplant

Bone marrow transplant is also known as Hematopoietic stem cell transplant in which healthy hematopoietic stem cells are administered in patients with dysfunctional or depleted bone marrow. Bone marrow transplantation is used extensively for the treatment of many disorders involving bone marrow elements, including severe combined immunodeficiency states, leukemias, osteoporosis, various inherited disorders, and, more recently, solid tumors.

Types of Bone Marrow Transplant are:

Autologous Stem Cell Transplant

In autologous stem cell transplant, patients' stem cells are collected from blood or bone marrow and stored, after giving the treatment stem cells are given back to the patient so that newly introduced stem cells can replace the cells that were harmed during treatment.

Allogeneic Stem Cell Transplant (Match Related)

It is a procedure in which a patient receives stem cells from a donor who has a match to replace their own stem cells that have been destroyed by treatment with radiation or high doses of chemotherapy. Best transplant outcomes can be achieved when the donor's HLA closely matches with the patient's HLA who can be within a family like a brother or sister.

Allogeneic Stem Cell Transplant (Match Unrelated)

When a patient does not have a close family relative with a close HLA match an unrelated donor can be found with a close HLA match for a stem cell transplant.

Allogeneic Stem Cell Transplant (Haploid)

In some cases a good HLA match can not be found then this type of allogeneic stem cell transplant can be an option in which the donor can be an exact half HLA match.

Why to do Stem Cell/ Bone Marrow Transplant in SUNACT

We have four pioneers in the field of stem cell/ bone marrow transplantation in India:

Dr. Saurav Bhave (Hematologist and Transplant Physician) was mentored by Dr. Mammen Chandy (Pioneer to bring bone marrow transplant in India and did the 1st successful transplant in 1984) is an expert in pioneering stem cell transplant in India. After extensive training at CMC Vellore, Dr. Saurav Bhave established the Tata Memorial Center, Kolkata stem cell transplant unit.

Dr. Ashay Karpe (Hematologist and Transplant Physician) trained at Tata Memorial Center, Kolkata and ACTREC, Mumbai under the guidance of Dr. Navin Khattry. Founded the bone marrow transplant unit at S L Raheja Hospital, Mumbai and pioneer to do the difficult transplant with high success rate

Dr. Bharat Bhosale has been known to create the transplant set up of prestigious Jaslok Hospital, Mumbai

Dr. Vijay M Patil has been trained under Dr. Navin Khattry at Tata Memorial Center, Mumbai and established the bone marrow transplant unit in Malabar Cancer Institute, Thalassery and Hinduja Hospital, Khar, Mumbai.

In terms of numbers, the SUNACT team has completed approximately 2000 stem cell/ bone marrow transplants in a short period with high success and survival rate.

SUNACT has a team of nursing staff well qualified from best institutes like Tata Memorial Hospital, Hinduja hospital for transplant care.

The SUNACT team has learned the most complex stem cell transplant procedures from global experts

A world-class, only one in asia, state-of-the-art transplant center, equipped with 1st GMP Modular Unit with complete HEPA filters provides a complete aseptic environment to the transplant patients

A dedicated experienced team of bone marrow transplant nurses, dieticians, physicians, and lab to provide the best outcome pre, and post bone marrow transplant

At SUNACT we perform the bone marrow/ stem cell transplant for the following disease

  • Multiple Myeloma
  • Myelodysplastic syndrome
  • Chronic Myeloid Leukemia
  • Acute Myeloid Leukemia
  • Lymphoma
  • Hematological malignancies
  • Solid Tumors like medulloblastoma, CNS

Frequently Ask Questions

BMT is commonly used in Leukemia, Lymphoma and Multiple myeloma. BMT can also be used in some type of Neuroblastoma.

YES. Treatment for adults and Childrens are similar although standard of care for children can be managed very carefully.

Every patient is unique and requires different amount of time depending upon their immunity development duration after the BMT. Your doctors determine if your immune system is strong enough, then you will be released from the hospital to continue recovery at home.

One of the most common complication is major chance of infection, and Short-term side effects of BMT may include fatigue, nausea, loss of appetite, hair loss, mouth sores and skin reactions. Another complication that may arise from allogenic transplant is graft-vs-host disease (GVHD).

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